Collage of testosterone medication, lab equipment, and classical bodybuilding imagery.

Testosterone therapy is trending. Who really needs it, and why?

Some clinicians are pushing to broaden testosterone use, but there is debate about its benefits and risks.

  • A Pd-catalysed method enables regio- and diastereoselective C–H alkylation of diverse alkenes using carboxylic acids, expanding synthetic access to complex substituted alkenes.

    • Triptesh Kumar Roy
    • Federico Maria Tamborini
    • Tobias Ritter
    ArticleOpen Access
  • Triplet excitons in OPVs can redissociate via the charge-transfer state into free carriers, reducing losses and improving efficiency, enabled by molecular design controlling singlet–triplet energetics through exciton delocalization.

    • Qian Li
    • Lingchen Kong
    • Alex K.-Y. Jen
    Article
  • The phase 1b NIVIPIT trial shows that in combined therapy with intravenous nivolumab (anti-PD1), intratumoural administration of ipilimumab (anti-CTLA4) offers improved safety and greater efficacy compared with intravenous delivery.

    • Lambros Tselikas
    • Sandrine Susini
    • Aurélien Marabelle
    ArticleOpen Access
  • Simulations performed using Quantinuum’s H2 trapped-ion quantum computer for observing thermalization on challenging timescales demonstrate the usefulness of digital quantum computers for investigating continuous-time dynamics in regimes that classical simulation methods find difficult.

    • R. Haghshenas
    • E. Chertkov
    • M. Foss-Feig
    Article
Various types of cancer cells.

Cancer

Cancer incidence is on the rise.
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